In the wake of the shootings many people who were generally already pro-gun control were greatly outraged. Some people expressed content that country music fans and presumed Trump voters and pro-gun people were the victims of the shooting. Others called for more gun control: bans on bump stocks, bans on semi-automatic rifles, increased fees, taxes and insurance on gun owners, criminal liability for people whose guns were stolen, limits on the number of weapons or ammunition any one man could purchase, warrantless searches of gun owners' homes, long prison sentences for someone caught with a banned gun, medical sign off to own a gun, government surveillance of anyone known to have more than x number of guns, lawsuits against the NRA or gun manufacturers, profiling of white men, registering of all guns nationwide, only particular types of guns (revolvers or shotguns) being allowed for civilian ownership, confiscation of all guns except for police or military use, and the repeal of the 2nd Amendment.
Amending the constitution requires 2/3 of the House and Senate to agree and 3/4 of the states. Or to put it another way if just 13 states disagree with rewriting the Constitution, it can't be done. Which states might oppose rewriting or eliminating the 2nd Amendment? Well for sure I think that Texas, Louisiana, Oklahoma, Arkansas, Mississippi, Alabama, Georgia, South Carolina, Missouri, Kansas, Nebraska, and North Dakota would oppose that move. That's 12 right there. Throw in just one more state, say Florida or Montana or Wyoming or Arizona or Indiana or Michigan, and that ends any talk of repealing the 2nd Amendment. It's usually at this point that people who want to repeal the 2nd Amendment become even more insulting and condescending to their opponents. They bemoan the fact the states which are sparsely populated or even worse, populated with the wrong kind of people, have just as much say in this process as states with larger or in their view more intelligent sorts of people.
Well that's too bad. That's the system we have. Per the Heller decision we have an individual right to own weapons. That doesn't mean the weapons can't be regulated or that specific ones can't be outlawed. Within limits, states are free to set up roadblocks to or regulations for gun ownership. But the idea of repealing the 2nd Amendment or banning all semi-automatics is a non-starter. The only sort of gun control which is politically possible is gun control at the state level. Some people might not like that but short of a sudden massive demographic change or an out and out civil war, that's how it's going to be. Guns are for better or worse, a part of American culture and civic religion.